Is Tau dispensable?

The heart provides energy to the circulation system. How powerful the muscle is played a key role in terms of cardiac function assessment. Tau is directly related to the active relaxation of the left ventricle, no alternatives so far.

A Brief History of Tau with Links You Might Need!

A Brief History of Tau

1976, Tau was born in John Hopkins.
1992, the first non-invasive try, Harvard.
1992, the first formula, with four assumptions, Harvard.
1993, another non-invasive try with decent data, Mayo Clinic.
1995, a similar strategy applied to AI patients, Japan.
1995, I published a MR based formula with one assumption.
1997, the Harvard formula was validated in Cleveland.
2005, Langer presented a non-zero asymptote model.
2008, I improved my MR based formulas, without assumption.
2008, I did a similar deduction for AI based Tau.
2008, Chen developed program for my formulas, free download.
2008, my poster in ASE 19th Annual Scientific Sessions.
2009, my poster in CSE forum.
2009, DF guideline (ASE) recommended Harvard formula.
2009, I gave my opinion about the guideline recommendation.
2009, "Response to Bai" from guideline writing group. It motivated me to create this Blog.
2010, Dr Wang and me presented general Tau.
2011-11-29, I gave a talk in National Capital Echo Round (Ottawa)
2016-03-29, I gave a talk at the Heart Institute, the North Hospital (Shenyang, China)
2016-04-01, I gave a talk at the Cardiac Function Dept., the 1st Clinical College, Chinese University of Medicine. (Shenyang, China)
2016, Symmetry inspired by the approach of Tau.
2017, Calculation of LAP (based on my formulas) got a Chinese Natural Science Founding.

Saturday, February 8, 2020

Questions Need to be Clarified...

  • Why not publish your paper in high AF journals?

Honestly, we tried a lot and most are failed. There is a dominant Tau non-invasive method from Harvard. Though the method doesn’t make sense, it made quite a few Tau “experts” who are always there to kill our papers. It is so easy for them to do so because they are influential researchers from influential institutions and they have already published their papers in influential journals. That is why we are calling for the retraction of these Tau papers with logic flaws. Before the retraction of fake ones, it is very tough for real ones to be accepted in high AF journals.

  • Tau can only be measured in patients with MR or AI, looks not very helpful?

Yes, there is limitation for Tau non-invasive measurement. We can put it this way, whenever we can measure PISA, we can measure Tau. However, Tau renders us a new vision over cardiac function assessment. This leads to the general Tau and the Symmetry of cardiac function assessment. Personally, I think the later will revolutionized our approach to the heart and the idea will become part of our cardiologist’s daily routine in the future.

  • What is the relation of Tau and our established Echo assessment of diastolic function?

I tried some measurements. Looks to me there is certain connection exists, roughly
Tau<40ms, normal
40<Tau<55, mild diastolic dysfunction
55<Tau<70, moderate diastolic dysfunction
70<Tau, severe diastolic dysfunction,
This is a primary impression, a multiple center research is welcomed to narrow down the meaningful numbers.

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