Is Tau dispensable?

Left ventricular diastolic time constant, Tau is the most established index to describe diastolic function. A Harvard method of Tau was invented by Dr JD Thomas has been dominant non-invasive Tau measurement for more than two decades. Now, Tau is dead clinically. Only when the logically flawed celebrity method is objectively reassessed and discarded, can Tau be given a chance. A new method is dawning and promising…

A Brief History of Tau with Links You Might Need!

A Brief History of Tau

1976, Tau was born in John Hopkins.
1992, the first non-invasive try, Harvard.
1992, the first formula, with four assumptions, Harvard.
1993, another non-invasive try with decent data, Mayo Clinic.
1995, a similar strategy applied to AI patients, Japan.
1995, I published a MR based formula with one assumption.
1997, the Harvard formula was validated in Cleveland.
2005, Langer presented a non-zero asymptote model.
2008, I improved my MR based formulas, without assumption.
2008, I did a similar deduction for AI based Tau.
2008, Chen developed program for my formulas, free download.
2008, my poster in ASE 19th Annual Scientific Sessions.
2009, my poster in CSE forum.
2009, DF guideline (ASE) recommended Harvard formula.
2009, I gave my opinion about the guideline recommendation.
2009, "Response to Bai" from guideline writing group. It motivated me to create this Blog.
2010, Dr Wang and me presented general Tau.
2011-11-29, I gave a talk in National Capital Echo Round (Ottawa)
2016-03-29, I gave a talk at the Heart Institute, the North Hospital (Shenyang, China)
2016-04-01, I gave a talk at the Cardiac Function Dept., the 1st Clinical College, Chinese University of Medicine. (Shenyang, China)
2016, Symmetry inspired by the approach of Tau.
2017, Calculation of LAP (based on my formulas) got a Chinese Natural Science Founding.

Sunday, December 13, 2020


One year ago, we realized the dominant Harvard Tau method has to be removed after so many rejections it caused. The reasons of rejection are “priority is not high enough”, “the Harvard Tau method is better”, “this is between Dr JD Thomas and you”…So,


The Harvard method of Tau calculation is incorrect


Early this year, Dr JD Thomas co-hosted the ASE Echo Hawaii 2020. We raised this Tau issue after lest it had any negative effects to this great event. Thereafter, we had asked several dozens of times the Harvard Tau had to be addressed formally. No reply. 


Dr JD Thomas, could you let us know what you are waiting for?


1.     Do you still think your formula is correct? We can debate this if that is the issue. Silence is not gold, it is kind of hit and run. 

2.     Early this year, JACC had a special issue about non-invasive assessment of DF. You were invited due to your celebrity ship but you did not mention your Tau formula. Weird! Tau is well accepted as the best index to describe DF. If you were planning to give up your formula, why you were selling it again in Dr AL Klein’s new book, Diastology?

3.     If you realized the theory is wrong, please formally address it. It leads to nowhere and any project based on it is a waste of time, energy, money, animals, and even human beings…also, it suffocates the other Tau research. We are the victims. 

4.     Everyone makes mistakes, especially during scientific investigation. It is OK. Yet, verification of incorrect theory needs manipulation of data. It is not OK, though pretty epidemic in biomedical research. On top of that, purposely covering up will make a scandal. 

5.     The best time to cut the losses is now. Please take a look at my personal website viewers distribution.


Hopefully, I don’t need to write Tau2021.

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