Tau is the most established index to describe diastolic function. Its measurement was commercialized in China in 2017, while in America it is demised in daily clinic. Why?

A Brief History of Tau with Links You Might Need!

A Brief History of Tau

1976, Tau was born in John Hopkins.
1992, the first non-invasive try, Harvard.
1992, the first formula, with four assumptions, Harvard.
1993, another non-invasive try with decent data, Mayo Clinic.
1995, a similar strategy applied to AI patients, Japan.
1995, I published a MR based formula with one assumption.
1997, the Harvard formula was validated in Cleveland.
2005, Langer presented a non-zero asymptote model.
2008, I improved my MR based formulas, without assumption.
2008, I did a similar deduction for AI based Tau.
2008, Chen developed program for my formulas, free download.
2008, my poster in ASE 19th Annual Scientific Sessions.
2009, my poster in CSE forum.
2009, DF guideline (ASE) recommended Harvard formula.
2009, I gave my opinion about the guideline recommendation.
2009, "Response to Bai" from guideline writing group. It motivated me to create this Blog.
2010, Dr Wang and me presented general Tau.
2011-11-29, I gave a talk in National Capital Echo Round (Ottawa)
2016-03-29, I gave a talk at the Heart Institute, the North Hospital (Shenyang, China)
2016-04-01, I gave a talk at the Cardiac Function Dept., the 1st Clinical College, Chinese University of Medicine. (Shenyang, China)
2016, Symmetry inspired by the approach of Tau.
2017, Calculation of LAP (based on my formulas) got a Chinese Natural Science Founding.
2024, JASE declined my Tau manu again.

Sunday, June 28, 2020

Tau Measurement in an Echo lab


Tau occurs during the isovolumic relaxation time (IVRT), when both the mitral and aortic valves are closed. To investigate any events within the left ventricle during this phase, we must rely on information provided by either mitral regurgitation (MR) or aortic insufficiency (AI).


In MR patient, 

In AI patient, 


While the classical concept of Tau remains foundational, the idea of a universal Tau is increasingly coming into focus. Below are the formulas currently proposed for calculating this universal Tau.


The beauty of Nature lies in her simplicity,” noted Dr. Quan Wang, a Fellow of the Royal Society of Canada, as he praised the proposed formulas.

Once again, the concept of a universal Tau is poised to unveil a new dimension—the symmetry in cardiac function assessment. When applied to four Doppler indices, 17 innovative approaches emerged from the shadows. Dr. Sherif Nagueh remarked that these approaches could be particularly valuable, especially in assessing right ventricular (RV) and diastolic function.

What lies ahead remains unknown. This new frontier is open to exploration, and all are welcome to test their ideas and insights.

Thus, it is fair to say: Tau may well revolutionize the assessment of cardiac function.

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