Why can Mindray make the first Tau-measurable ultrasound machine?

In 1976, the left ventricular diastolic time constant, Tau was found at John Hopkins. According to the definition, it can be accurately measured in a catheter lab, and soon, Tau was well accepted as the best index to describe left ventricular diastolic function. For the possibility of measuring it in the Echo lab and make it more accessible to clinicians, intensive investigation was done in 1990s at Harvard, Mayo Clinic, Cleveland, Osaka University, etc.

However, Mindray, the largest Chinese medical equipment company has just launched its Tau-measurable high-end ultrasound machine DC80. How? Why?

Mindray had just launched a high-end ultrasound machine DC80, which is the first Tau-measurable ultrasound machine in the world.

A Small Step in Math, A True Stride in Cardiology

With the progress of Doppler and modern computer technology, I believe that only a few RBCs’ leaking will be needed to give us a much understandable and clear regurgitation curve. Theoretically, merely a short part of the curve is enough to calculate the Tau. As long as we are allowed to choose 3 points from within the definition field, we can use the updated formulas to proceed. Let’s assume the 3 points are a (v_a, t_a), b (v_b, t_b) and c (v_c, t_c) from left to right. The updated formulas are:

All Tau(s) Calculation Formulas

"The beauty of nature lies in her simplicity."

--- Dr Quan Wang

-dp/dt max is equivalent to Tau

Recently, an editorial (1) from Circulation Heart Failure claimed “Tau derived from the monoexponential model is less dependent on loading conditions than peak -dp/dt and has been used as a reliable index for LV relaxation in many clinical and experimental studies.”

I think –dp/dt max and Tau are the SAME in terms of clinical significance.

CAAM, a clinical call for help from the echo engineers.

Accurate measurement of time intervals is critically important for successful Tau calculation. Garbage in, garbage out. But don't hesitate to move forward. We just need something like computer aided accurate measurement, CAAM. I figured out this word. :)

My response to "response to Bai"

Response to Bai from the ASE AND EAE DIASTOLOGY WRITING GROUP

"Response to Bai" reiterated why those 5 assumptions are acceptable. However, I developed my formulas without assumption.