Is Tau dispensable?

Left ventricular diastolic time constant, Tau is the most established index to describe diastolic function. A Harvard method of Tau was invented by Dr JD Thomas has been dominant non-invasive Tau measurement for more than two decades. Now, Tau is dead clinically. Only when the logically flawed celebrity method is objectively reassessed and discarded, can Tau be given a chance. A new method is dawning and promising…

A Brief History of Tau with Links You Might Need!

A Brief History of Tau

1976, Tau was born in John Hopkins.
1992, the first non-invasive try, Harvard.
1992, the first formula, with four assumptions, Harvard.
1993, another non-invasive try with decent data, Mayo Clinic.
1995, a similar strategy applied to AI patients, Japan.
1995, I published a MR based formula with one assumption.
1997, the Harvard formula was validated in Cleveland.
2005, Langer presented a non-zero asymptote model.
2008, I improved my MR based formulas, without assumption.
2008, I did a similar deduction for AI based Tau.
2008, Chen developed program for my formulas, free download.
2008, my poster in ASE 19th Annual Scientific Sessions.
2009, my poster in CSE forum.
2009, DF guideline (ASE) recommended Harvard formula.
2009, I gave my opinion about the guideline recommendation.
2009, "Response to Bai" from guideline writing group. It motivated me to create this Blog.
2010, Dr Wang and me presented general Tau.
2011-11-29, I gave a talk in National Capital Echo Round (Ottawa)
2016-03-29, I gave a talk at the Heart Institute, the North Hospital (Shenyang, China)
2016-04-01, I gave a talk at the Cardiac Function Dept., the 1st Clinical College, Chinese University of Medicine. (Shenyang, China)
2016, Symmetry inspired by the approach of Tau.
2017, Calculation of LAP (based on my formulas) got a Chinese Natural Science Founding.

Saturday, March 13, 2021

Doppler spectrum precision measurement will reveal more secrets of hemodynamics


For many years, the Doppler spectrum was measured manually in most of times. Their shortcomings include time-consuming, less accuracy and unacceptable variation between operators. A promising automatic measurement is dawning thanks to the Doppler spectrum enveloping widely used in vascular ultrasound, yet the technology needs dramatically improved. In the point of view of engineering, a more accurate measurement is doable with the neck breaking developing computer technology. This issue is overlooked mainly for sake of barely no clinical demand. And now, it is brought in front of us due to measurement of Tau. Tau, left ventricular diastolic time constant is an established best index to describe diastolic function. The non-invasive measurement of tau theory is perfect, [1,5] the practice lags behind because the Doppler measurement accuracy is not satisfactory. From other point of view, less accurate measurement can lead to weird conclusions, even for some celebrities. [6,7]

Wednesday, January 27, 2021

Cao in My Eyes and Beyond

Recently, several articles from top scientific journals are the culmination of years of cracking down academic fraud campaign. Unfortunately, Cao Xuetao became the key role. With the absolute dominant influence of the journals over research area, Cao is almost the most infamous scientist right now. The Chinese Ministry of Science and Technology was also blamed for failing to handle the whole process properly.

Sunday, December 13, 2020


One year ago, we realized the dominant Harvard Tau method has to be removed after so many rejections it caused. The reasons of rejection are “priority is not high enough”, “the Harvard Tau method is better”, “this is between Dr JD Thomas and you”…So,

Wednesday, November 11, 2020

The 7th letter to Dr JD Thomas

Dear Dr Thomas,

This is the 7th letter to you. Because all the previous ones were ignored, it might be a good idea to go public.

Please formally address your Tau formula which is logically flawed in our opinion.

Verification of flawed theory needs manipulated data, which is a hot topic in the whole medical publishing industry right now.

Inspired by the recent American election, let’s give each other a chance by exchanging ideas.

We might be wrong, please show us the right way.